Q&A 7 – Adderall Safety, Formaldehyde VS PCP, & Harmala Alkaloids (And More)


If you’d like to skip to a specific question
or comment, you can find the time stamps in the description. The Drug Classroom runs entirely on donations. If you’d like to support, please visit Patreon.com/TheDrugClassroom “In your opinion, what’s the safest psychedelic
to take psychologically?” There’s not a specific psychedelic I can point
to as the safest from a psychological standpoint. Though there are psychedelics where the overall
rate of difficult experiences might be lower. Some of those include 2C-B, AL-LAD, and 4-Hydroxy-MET. It’s clearly still possible to have difficult
experiences and it’s not even clear that the rate is notably lower with those drugs. But, I’m inclined to say a common dose of
2C-B will generally be easier to handle than a common LSD dose. Although short-term difficult effects aren’t
uncommon with psychedelics, lasting problems are rare regardless of the psychedelic. Issues like psychosis, depression, and HPPD
might vary between substances, but they’re not typical responses by any means with the
class overall. You can also reduce the chance of acute psychological
difficulties with psychedelics in general by using a common dose. If you’re new to the category, using a low
dose is wise. There are likely benefits to picking a shorter-acting
drug, such as 2C-B, over a longer-acting drug like LSD. “Based on your life experiences, if you had
to choose only one drug to take in your entire life, what would it be?” No specific drug comes to mind. Salvia divinorum has been the most interesting
for me, so that’s one possibility. I use caffeine more than any other substance,
though I don’t find it remarkably helpful and tolerance does build. Tea would currently be my go-to substance
for daily use. It’s also possible I would pick a nootropic. I’m beginning to test more from that category,
so I may come across something that stands out as useful. “Is Adderall safe to use? My concentration and focus are weak, and I
want to study harder and more than before?” This depends on how adderall is being used. Taking it once or twice per week at a common
dose isn’t going to be physically dangerous for otherwise healthy people. It should also be used early enough to not
infringe upon sleep. I consider it preferable not to end up relying
on the substance for studying or taking tests. So I don’t think it’s wise to be in a situation
where you use Adderall every time you need to study, write a paper, or take a test. Also, if you’re in a situation where you have
trouble focusing, Adderall needn’t be the potential solution you immediately jump to. You should make sure your sleep, exercise,
diet, and stress levels are in check. Meditation can also be helpful in this area. And you may benefit from seeing a physician
to see if you potentially have ADHD. Though most people with focus issues don’t
have ADHD. Other pharmacological options outside of amphetamine,
such as tea, also exist. I’d recommend exploring those before considering
amphetamine. “Formaldehyde is or is not PCP?” Formaldehyde definitely isn’t PCP. As you can see from their structures, they
aren’t even similar. I’m really not sure where this idea came from. It’s presumably from PCP at times being referred
to as “embalming fluid.” And formaldehyde is an embalming chemical. Regardless, it’s an unhelpful name for the
drug and PCP isn’t even close to formaldehyde. “Harmala alkaloids, harmine and harmaline,
are not MAOIs. They are RIMAs. There are similarities but they are not the
same. MAOIs are far riskier and last longer. Please cover that in a video about ayahuasca.” Harmine and Harmaline are MAOIs. And it can be dangerous to combine them with
other substances acting in a pro-serotonin manner. You can certainly classify MAOIs further,
just as you can for many drug groups. It’s accurate to say call them reversible
inhibitors of monoamine oxidase A, but that’s in addition to being classified as MAOIs. This means they’re selective for MAO-A over
MAO-B and they operate in a reversible manner. Those qualities limit their activity period
and interaction potential. A drug like harmine is less potentially problematic
than phenelzine, for example. RIMAs in general are less problematic when
it comes to combining them with tyramine. Though that doesn’t mean there are no safety
precautions. Overall, there are definitely categories within
MAOIs. Selective or nonselective. Reversible or irreversible. But, they’re all MAOIs. If you have any questions, feel free to leave
them in the comments section. Also, if you have questions for future Q&A
videos, you can put them in the comments or send them via email, Facebook, or Twitter. If you’d like to support The Drug Classroom,
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